Teneurins

According to Wikipedia,

Teneurins are transmembrane proteins. The name refers to “ten-a” (from “tenascin-like protein, accessory”) and “neurons”, the primary site of teneurin expression.

Teneurins are highly conserved between Drosophila, C. elegans and vertebrates. In each species they are expressed by a subset of neurons as well as at sites of pattern formation and morphogenesis. In Drosophila, a teneurin known as ten-m or Odz is a pair-rule gene, and its expression is required for normal development. The knockdown of teneurin (ten-1) expression in C. elegans with RNAi leads to abnormal neuronal pathfinding and abnormal development of the gonads.

And according to this article,

Teneurins are a unique family of transmembrane proteins conserved from C. elegans and D. melanogaster to mammals. In vertebrates there are four paralogs (teneurin-1 to -4), all of which are expressed prominently in the developing central nervous system.

So why mention these proteins?

 

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3 responses to “Teneurins

  1. Where the hell have you been?! You had me scared sh..tless that something happened to you! Don’t do that!

  2. Sorry. I’ve just been incredibly busy.

  3. Next time say something like, “I’ll be incredibly busy for a while, so don’t worry if you don’t see anything new from me.”

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