Let me show you another example of that subtle front-loading pattern. This time, we’ll use a published paper that discusses a protein I have previously tagged as a candidate for front-loading:
Pincus D, Letunic I, Bork P, Lim WA. 2008. Evolution of the phospho-tyrosine signaling machinery in premetazoan lineages. Proc Natl Acad Sci U S A. 105(28):9680-4.